The PGH Medical Foundation, Inc., is a non-stock, non-profit organization which was established to assist the Philippine General Hospital (PGH) in achieving its mission of providing excellent health care for its indigent patients. It serves as a conduit of donations coming from various civic-minded individuals, corporations, foundations and other funding agencies.

The Foundation was organized in 1997 by then PGH Director Antonio Montalban, together with some concerned doctors of the hospital and prominent community leaders. It became fully operational only in 2003 when it became a major partner of PGH. The foundation is a registered donee institution certified by the Bureau of Internal Revenue (BIR), thus allowing it to give Certificates of Donation entitling donors to tax credits.